First Reliance Bank: branch locations

First Reliance Bank is an FDIC-insured bank with 10 branches in 1 state in our list. Its main office address in the FDIC records is 2170 W Palmetto St, Florence, SC 29501.

Contact details

Main office2170 W Palmetto St, Florence, SC 29501
Official websitefirstreliance.com
FDIC certificate35214

The website address is the one the bank reported to the FDIC. Phone numbers are not part of the FDIC data, so use the number on your card or the bank’s own website.

Where First Reliance Bank has branches

StateBranches
South Carolina10

All First Reliance Bank branches

Showing 10 of 10

CityStateBranchAddressZIPMap
Columbia SC Downtown Columbia Branch 1901 Main St 29201 Map
Florence SC First Reliance Bank (main office) 2170 W Palmetto St 29501 Map
Florence SC Second Loop Branch 411 2nd Loop Rd 29505 Map
Greenville SC Greenville Downtown Branch 500 E Washington St 29601 Map
Lexington SC Lexington North Lake Dr Branch 801 N Lake Dr 29072 Map
Mount Pleasant SC Mount Pleasant Branch 800 S Shelmore Blvd 29464 Map
Myrtle Beach SC Myrtle Beach - Mayfair St Branch 3842 Mayfair St 29577 Map
Myrtle Beach SC Myrtle Beach Brach 507 21st Ave N 29577 Map
Simpsonville SC Simpsonville Branch 150 Highway 14 29681 Map
West Columbia SC Sunset Blvd, West Columbia Branch 2805 A Sunset Blvd 29169 Map

Source: FDIC BankFind Suite, retrieved 2026-09-20. This site is independent and is not affiliated with First Reliance Bank. Confirm branch details with the bank.

Frequently asked questions

How many branches does First Reliance Bank have?

Our list has 10 branches of First Reliance Bank, in South Carolina (10). The number changes as branches open and close.

Where is First Reliance Bank headquartered?

The FDIC lists the main office at 2170 W Palmetto St, Florence, SC 29501.

Is First Reliance Bank FDIC-insured?

According to the FDIC BankFind data, First Reliance Bank is an active FDIC-insured institution (certificate number 35214). Confirm any bank you plan to use in the FDIC’s BankFind tool.